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Non-Invasive Prenatal Screening

Prenatal Safe - Nitsos Lab

PrenatalSafe®, a non-invasive prenatal test, analyzes cell-free fetal DNA isolated from a maternal blood sample. It analyzes the most common fetal chromosomal abnormalities detected in pregnancy and associated with chromosome 21 (Down syndrome), chromosome 18 (Edwards syndrome), chromosome 13 (Patau syndrome) and sex chromosomes (X and Y), for instance Turner syndrome, Klinefelter syndrome, triple X syndrome and Jacobs syndrome.

It is a simple, fast, safe and reliable test.

  • It requires a small amount of blood, collected from pregnant women at the 10th week of gestation.
  • It is non-invasive and thus, eliminates the possibility of spontaneous abortion associated with traditional invasive prenatal screening techniques, such as amniocentesis and chorionic villus sampling.
  • It has a sensitivity of >99% in detecting chromosomal aneuploidies (Trisomy 21, Trisomy 18, Trisomy 13, Monosomy X) with false positive results <0.1%.
  • High resolution FAST technology is used, providing results in only 5 working days, maintaining the same levels of sensitivity and specificity as standard analysis.

Testing is performed using massively parallel DNA sequencing technology to count the copy number of the chromosomes under investigation. A calculation method is then applied to determine whether there are more or fewer copies of these chromosomes in the fetus.